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36 Cards in this Set

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Name 3 factors contributing to GERD.
1) drinking alcohol

2) smoking cigarettes

3) consuming various foods (high fat content, caffiene, citrus, and spices)
Therapy for GERD
Using a combination of medications
Antacid agents used to treat GERD (2):
1) aluminum hydroxide-magnesium carbonate (Gaviscon ES)

2) magnesium hydroxide (Milk of Magnesia)
H2 antagonists to treat GERD (2):
1) cimetidine (Tagamet)

2) ranitidine (Zantac)
Name 3 agents used to treat GERD.
1) antacids
2) H2 antagonists
3) Proton pump inhibitors
Name 4 therapeutic uses of ranitidine (Zantac).
1) active duodenal ulcers
2) benign gastric ulcers
3) long-term prevention of duodenal ulcers
4) GERD
What are 2 proton pump inhibitor agents for GERD (2)?
1) Iansoprazole (Prevacid)

2) omeprazole (Prilosec)
Which agents for GERD are indicated for short-term treatment?
1) Iansoprazole

2) omeprazole
What is a primary side effect of omeprazole?
diarrhea
Which drug is indicated for short-term therapy of ulcers and esophagitis?
Iansoprazole
Name 3 common types of ulcers.
1) Gastic
2) Duodenal
3) Stress
What is the prevalence of gastric ulcers?
1) occur more in men than women

2) smokers

3) populations in Western Hemispheres
What is a duodenal ulcer?
a peptic lesion in the duodenum
Duodenal ulcers are more difficult to treat than gastric ulcers. Why?
It is difficult to get medication to the duodenum.
What causes stress ulcers?
Severe physiological stress
Patients in the ICU usually get stress ulcers. What do they receive to relieve these ulcers?
prophylactic therapy of H2 antagonists
Which 4 drugs may cause ulcers?
1) alcohol
2) aspirin
3) anti-inflammatory drugs
4) corticosteroids
What is an adverse effect of alcohol?
irritating to the GI tract
What is an adverse effect of aspirin?
irritating to the GI tract
What is an adverse effect of anti-inflammatory drugs?
reduce production of mucus
What is an adverse effect of corticosteroids?
reduce the mucosal barrier
What is the cause of most peptic ulcer?
H. pylori
How does H.pylori cause peptic ulcers?
it secretes enzymes that neutralize stomach acid.
What is the mainstay therapy for pharmacologic treatment of H. pylori?
Antibiotics
-mixed w/antacid or proton pump inhibitor
Name 2 antibiotic agents for H. pylori.
1) amoxicillin

2) tetracycline
NON-OPIOIDS CARD SET

NAME 3 NON-OPIODS.
1) SALICYLATES
2) NSAIDS
3) ADJUNCTS
NON-OPIOID CARD SET

GIVE AN EXAMPLE OF A SALICYLATE.
ASPIRIN (BAYER)
NON-OPIOID CARD SET

WHAT DOES NSAID STAND FOR?
NON-STEROIDAL ANTI-INFLAMMATORY DRUGS
NON-OPIOID CARD SET

GIVE 4 EXAMPLES OF NSAIDS.
1) IBUPROFEN (MOTRIN, ADVIL)

2) NAPROXEN (NAPROSYN)

3) NAPROXEN SODIUM (ALEVE)

4) KETORALAC (TORADOL)
NON-OPIOID CARD SET

NSAIDS COMPETE WITH _____ FOR _________________.
-ASPIRIN

-PROTEIN BINDING SITES
NON-OPIOID CARD SET

NAME 3 THINGS THAT NSAIDS HELP TO DECREASE.
1) FEVER
2) INFLAMMATION
3) PAIN
NON-OPIOID CARD SET

WHICH NSAID DOES NOT HELP DECREASE INFLAMMATION?
ACETAMINOPHEN
NON-OPIOD CARD SET

WHICH ENZYME IS RESPONSIBLE FOR THE SYNTHESIS OF PROSTAGLANDINS AND THROMBOXANE A?
CYCLOOXYGENASE (COX)
NON-OPIOD CARD SET

WHAT NSAID INHIBITS THE SYNTHESIS OF CYCLOOXYGENASE?
ASPIRIN
NON-OPIOID CARD SET

WHAT ARE THE NEGATIVE EFFECTS OF ASPIRIN?
1) GI ULCERATION
2) INCREASE BLEEDING
3) DECREASE RENAL ELIMINATION
4) DECREASE UTERINE CONTRACTION DURING LABOR
NON-OPIOID CARD SET

HOW IS ACETAMINOPHEN (TYLENOL) DIFFERENT FROM ASPIRIN?
ACETAMINOPHEN ONLY INHIBITS SYNTHESIS OF CNS PROSTAGLANDINS.

IT DOES NOT HAVE PERIPHERAL SIDE EFFECTS LIKE ASPIRIN.