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9 Cards in this Set

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Ways to reduce the evolution of antibiotic resistance


What the spot overlay version of the Ames Assay is and how it worked. Know what was expected in each section on the plate including the positive and negative controls.

Look at notes

Know what the Ames plate incorporation assay is and how it works.

uses bacteria to test whether a given chemical can cause mutations in the DNA of the test organism

Know what a dose response is

describes the change in effect on an organism caused by differing levels of exposure

Know how to spot each type of mutation in a sequence of DNA- base pair substitution, frameshift, deletion/insertion


What a gel electrophoresis is and how is works

Gel electrophoresis works by using an electric current to pass DNA samples through a gel. The gel acts like a sieve allowing smaller DNA molecules to migrate through the gel quicker than larger molecules. Thegel is then visualised under UV light where DNA samples appear as bands.

What a reverse mutation assay is

Mutation which reverts back to its original

What a carcinogen is

having the potential to cause cancer

How to tell if a substance is mutagenic and what substance is most mutagenic from looking at a chart of data