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30 Cards in this Set

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  • Back
Most everything is regulated by
Isoleucine
What happens in allosteric inhibition?
Active site changes shape
---> substrate cannot bind
What is an allosteric site?
Additional site on enzyme where ONLY a regulatory molecule can bind
(NOT AN ACTIVE SITE)
What happens to the substrate when the inhibitor binds to the active site?
Substrate cannot bind (competitive inhibition)
What term means the reaction does not occur?
Inhibit
Non protein, organic molecules
- often carrier/ transport molecules (vitamins)
Coenzyme
What 2 factors affect enzyme function?
Temperature
pH
Non protein enzyme helpers
- usually inorganic (iron)
Cofactor
When shape changes to hold substrate?
Induced fit
An induced fit where the enzyme changes shape after substrate binds
Active site
How do enzymes catalyze biochemical reactions?
Hold reactant in position that reaction is most likely to occur
How do enzymes catalyze reactions?
Decrease amount of NRG needed, lower course of reaction
Free NRG needed to start a reaction
Activation energy
Chemical reaction
Anabolic (small to big)
Needs NRG
NON-SPONTANEOUS
Endergonic reaction
Chemical reaction with +🔺G
Endergonic
Chemical reaction
Catabolic (big to small)
Gives NRG
SPONTANEOUS
Exergonic (NRG is EXiting)
Chemical reaction with -🔺G
Exergonic
Processes with a positive 🔺G are
Non spontaneous
Processes with a negative 🔺G are
Spontaneous
What does 🔺G stand for?
What is it's formula?
Gibbs Free Energy
G(products) - G(reactants)
This occurs with NRG in a chemical reaction (requires NRG)
Non spontaneous processes
This occurs without NRG input and increased entropy... a chemical reaction
Spontaneous processes
What is entropy (s)?
Disorder/ randomness
What is the second law of thermodynamics?
Transformation of NRG increases entropy of the universe
In the first law of thermodynamics:
Energy can _______
Energy cannot______
NRG can transfer
NRG cannot be created/ destroyed
What is the first law of thermodynamics?
Total NRG in the universe is constant
Study of NRG and it's transformations
Thermodynamics
Big to small
Catabolic pathways
Small to big
Anabolic pathways
Proteins that catalyze a reaction
Enzyme