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22 Cards in this Set

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A variation of red blood cell size is known as

Anisocytosis


- Appear smaller than normal mature erythrocyte.


- More dense staining than normal mature erythrocyte.


- No central zone pallor.


- Associated with immune-mediated hemolytic anemias.


Spherocytes

Heinz Bodies



Round structure representing denatured hemoglobin.


Up to 5% normal in cats.

Target cells

Howell Jolly Bodies



Basophilic nuclear remnants seen in young erythrocytes in response to anemia; removed by the spleen.

Name the erythroid maturation series in proper order.

1. Rubriblast


2. Prorubricyte


3. Rubricyte


4. Metarubricyte


5. Reticulocyte


6. Erythrocyte

Describe canine RBC shape

Discocytic, biconcave disc.


Central pallor due to thin layer of hemoglobin.


Shape facilitates better transporting of oxygen.

Signs of regeneration

1. Polychromasia


2. Anisocytosis


3. Nucleated RBCs


4. Howell Jolly Bodies

Rouleaux



A groping of erythrocytes in stacks; seen with increased fibrinogen or globulin.

Agglutination



An antibody coats the erythrocyte causing bridging and clumping.

Basophilic Stippling



Presence of small, dark-blue bodies within the erythrocyte.


Seen in lead poisoning.

Nucleated RBC



Cells released into circulation early during anemia.

Schistocyte



RBC fragments; usually from shearing of the red cell by intravascular trauma; DIC

Spherocytes

What is the difference between feline and canine RBCs?

Cat red blood cells are smaller than canine red blood cells and they have limited central pallor.

Acanthocytes: Irregular, spiculated red cells with few unevenly distributed surface projections of various length and diameter.


Schistocyte: RBC fragments; usually from shearing of the red cell by intravascular trauma. DIC.


RBCs with a smaller than normal diameter and decreased MCV; seen in iron deficiency.


Akitas may have this type of cells.

Microcytes

RBCs that are larger than normal with an increased MCV.


Poodles may have this type of cells.

Macrocytes

RBC that exhibit a bluish tint when stained with Wright's stain; organelles remain in cytoplasm indicating young cells.

Polychromasia

RBC changes from disc shape to spheres with projections; result of pH change due to slow drying of blood films.

Crenation

What are the three basic classes of etiological anemia?

1. Blood loss.


2. Hemolysis.


3. Inadequate production.


What is macrocytosis?

Increase of the MCV seen in young RBCs.